The Role of the Craniocervical Junction in Craniospinal Hydrodynamics and Neurodegenerative Conditions
The craniocervical junction (CCJ) is a potential choke point for craniospinal hydrodynamics and may play a causative or contributory role in the pathogenesis and progression of neuro-degenerative diseases such as Alzheimer’s disease, Parkinson’s disease, MS, and ALS, as well as many other neurological conditions including hydrocephalus, idiopathic intracranial hypertension, migraines, seizures, silent-strokes, affective disorders, schizophrenia, and psychosis. The purpose of this paper is to provide an overview of the critical role of the CCJ in cranio-spinal hydrodynamics and to stimulate further research that may lead to new approaches for the prevention and treatment of the above neuro-degenerative and neurological conditions.
Effect of Atlas Vertebrae Realignment in Subjects with Migraine: An Observational Pilot Study
Introduction. In a migraine case study, headache symptoms significantly decreased with an accompanying increase in intracranial compliance index following atlas vertebrae realignment. This observational pilot study followed eleven neurologist diagnosed migraine subjects to determine if the case findings were repeatable at baseline, week four, and week eight, following a National Upper Cervical Chiropractic Association intervention. Secondary outcomes consisted of migraine-specific quality of life measures. Methods. After examination by a neurologist, volunteers signed consent forms and completed baseline migraine-specific outcomes. Presence of atlas misalignment allowed study inclusion, permitting baseline MRI data collection. Chiropractic care continued
for eight weeks. Post intervention re-imaging occurred at week four and week eight concomitant with migraine-specific outcomes measurement. Results. Five of eleven subjects exhibited an increase in the primary outcome, intracranial compliance; however, mean overall change showed no statistical significance. End of study mean changes in migraine-specific outcome assessments, the secondary outcome, revealed clinically significant improvement in symptoms with a decrease in headache days. Discussion. The lack of robust increase in compliance may be understood by the logarithmic and dynamic nature of intracranial hemodynamic and hydrodynamic flow, allowing individual components comprising compliance to change while overall it did not. Study results suggest that the atlas realignment intervention may be associated with a reduction in migraine frequency and marked improvement in quality of life yielding significant reduction in headache-related disability as observed in this cohort. Future study with controls is necessary, however, to confirm these findings. Clinicaltrials.gov registration number is NCT01980927.
By Dr. Alan Fox
Proven ways to end migraine headaches once and for all without drugs. Learn about the 3 hidden headache triggers every migraine sufferer should know about. Find out the easiest way to alter your daily routine to stop the pain for good and what the connection is between head, neck injuries and migraines.
Chiropractic Orthospinology can successfully affect a wide range of challenges to your general health. This health link is a comprehensive list of research, published or presented, that documents the efficacy of various Upper Cervical chiropractic techniques to correct or improve a wide range of disorders and diseases such as ADD/ADHD, Autism, Back Pain, Chronic Fatigue/Fibromyalgia, Headaches, Immune Function and a host of other secondary conditions.